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Procalcitonin (PCT)

Number:LD-PCT-01
Keyword:
Procalcitonin (PCT)
Product description

Project Introduction

PCT is a parameter for the diagnosis and monitoring of bacterial inflammatory disease infections. PCT can be used as an acute parameter to differentiate between bacterial and non-bacterial infections and inflammation, as a basis for monitoring patients at risk for infection (eg, post-surgery and post-organ transplant periods of immunosuppression, post-multiple trauma) and Patients requiring intensive care; at the same time, to detect the systemic impact of bacterial infection or to detect septic complications, to evaluate the clinical course and prognosis of severe inflammatory disease.

Features

High sensitivity: The functional sensitivity of PCT reagent is less than or equal to 0.3ng/mL.

Rigorous traceability: The traceability system is established through the primary calibrator of procalcitonin PTN47 established by BRAHMS.

Mass production upgrade: The unique "one-pot cooking" process makes it easy to supply thousands of liters of other reagents in a single batch.

Excellent correlation: 50 samples of Roche chemiluminescence were tested, and the correlation coefficient r≥0.95.

5) Good compatibility: Compatible with a variety of serum, plasma, whole blood, compatible with various biochemical analyzers, specific protein analyzers, blood cell analyzers and other instruments.

Liding self-produced OEM inflammation series star reagent recommendation

article number

Reagent ratio

Reference range

Linear range

C-reactive protein (CRP)

LD-hsPCT-01

R1:R2=3:1

0-0.5ng/mL

0-20ng/mL

LD-PCT-01

R1:R2=3:1

0-0.5ng/mL

0-60ng/mL

LD-CRP-S

customizable

Serum Amyloid A (SAA)

LD-SAA-OEM

R1:R2=4:1

0-10 mg/L

2-300 mg/L

LD-SAA-S

Can be customized according to the machine

C-reactive protein (CRP)

LD-CRP-01

R1:R2=4:1

0-10 mg/L

2-200 mg/L

LD-CRP-02

R1:R2=1:1

0-5 mg/L

0.5-320 mg/L

LD-CRP-S

customizable

Heparin-binding protein (HBP)☆

LD-HBP-OEM

R1:R2=4:1

0-10ng/mL

2-200ng/mL

PCT antigen

Through the recombinant expression of natural PCT protein, the company has developed a recombinant PCT protein with excellent stability, and with the company's supporting antigen preservation solution, it can ensure that the protein is in a liquid state and is heated at 37 ℃ for 7 days, and the loss of protein activity does not exceed 10 %.

The following uses the company's procalcitonin (PCT) detection kit (latex-enhanced immune turbidimetric method) to test the stability of the antigen. The results show that the accelerated inspection at 37 °C for 7 days, the deviation is ±10% Within 2-8 ℃ storage conditions for 2 months, the deviation is within ± 10%.

37℃ thermal stability

 

1

 

2-8℃ stability

 

1

 

Liding self-produced PCT antigen recommendation:

product name

English abbreviation

article number

PCT antigen 

PCT Ag

LD-Ag-PCT

PCT Antigen Diluent 

PCT Dilution

LD-D-PCT-L

PCT antibodies

product name

English abbreviation

article number

Mouse anti-human PCT monoclonal antibody 01 

PCT mAb 01

LD-mAb-PCT-01

Mouse anti-human PCT monoclonal antibody 02 

PCT mAb 02

LD-mAb-PCT-02

Mouse anti-human PCT monoclonal antibody 03 

PCT mAb 03

LD-mAb-PCT-03

Mouse anti-human PCT polyclonal antibody 04 

PCT gpAb 04

LD-gpAb-PCT-04

Using our company's antibodies can be directly adapted to our company's latex microspheres, and the effect is better!

product name

English abbreviation

article number

Microspheres 400

Latex 400

LD-cLATEX-400

 

particle size

380-420 nm

Carboxyl content

0.08-0.10mmol/g

solid content

10.0-10.5%

 

Recommended process

 

1

 

Reagent performance

Features of the top product:

name

LeadingBio

Linear range

0.5-50 ng/mL

Adaptation parameters

3:1 etc. (R1/R2)

sample type

serum

Precision

The intra-assay CV≤5.0%; the inter-assay relative deviation R≤10.0%.

other

Can also provide supporting calibrators, quality control, antigen and antibody, etc.

Linear:

 

1

 

Precision:

 

Inter-assay precision

within-assay precision

(ng/mL)

Low

High

Low

High

N

10 (batch)

10 (batch)

20 times)

20 times)

AVE

0.45

30.2

0.49

31.1

CV

4.7%

1.4%

3.0%

0.9%

The inter-assay and intra-assay precision of the reagents was good.

Reagent comparison:

 

1

 

Good clinical consistency between reagents and imported reagents

37℃ stability

 

1

 

2-8℃ Stability:

 

1

 

2-8 degrees Celsius open bottle stability

 

1

 

The reagent has good stability, accelerated investigation at 37°C for 7 days, the deviation is within ±10%; 2-8°C open bottle condition is stored for 1 month, and the deviation is within ±10%.

HOOK:

 

1

 

Reagent hook critical concentration ≥ 70ng/mL

We could not find any corresponding parameters, please add them to the properties table
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